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Image Search Results
Journal: Nutrients
Article Title: Integrated Proteomics and Metabolomics Reveal the Direct Hepatic Protection of Propionate Against Alcoholic Liver Disease via the RGN-PPARα Pathway
doi: 10.3390/nu18050872
Figure Lengend Snippet: Effect of propionate on RGN-PPARα signaling. ( A ) PPI network of DEPs between propionate-treated group and EtOH group. ( B , C ) Predicted binding modes of propionate to the active domain of RGN: ( B ) three-dimensional and ( C ) two-dimensional interaction diagrams. ( D ) Representative Western blot images of RGN, PPARα, p-AMPK, and ACOX1 protein expression in the liver. ( E ) Quantification normalized to the indicated loading controls (RGN/PPARα to β-actin; p-AMPK to AMPK; and ACOX1 to GAPDH). The data are presented as means ± SEM (n = 4). * p < 0.05; ** p < 0.01.
Article Snippet: Primary antibodies, including β-actin (#66009-1-Ig), CPT1A (#15184-1-AP), SREBP-1 (#14088-1-AP), ACC1 (#21923-1-AP), ACOX1 (#83731-2-RR), PPARα (#66826-1-Ig) and
Techniques: Binding Assay, Western Blot, Expressing